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Virus infection and allergy in the development of asthma: What is the connection?Information is accumulating which implicates airway inflammation resulting from respiratory viral infections, acting against a background of atopy.
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Effect of early carriage of streptococcus pneumoniae on the development of pneumococcal protein-specific cellular immune responses in infancyThe aim of this study was to examine the relationship between nasopharyngeal pneumococcal colonization in early life and the development of T cell responses.
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Maternal serum vitamin D levels during pregnancy and offspring neurocognitive developmentThe objective was to determine the association between maternal serum 25(OH)-vitamin D concentrations and behavioural, emotional and language outcomes...
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Comparison of neonatal T regulatory cell function in Papua New Guinean and Australian newbornsWe compared neonatal T reg from children born in western conditions (Australia) with those of neonates born in high microbial conditions (Papua New Guinea)...
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A novel role for interleukin-1 receptor signaling in the developmental regulation of immune responses to endotoxinSuggests that IL-1R1 expression provides an additional level of Myd88-dependent signaling during this period of heighted susceptibility to infection.
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T-cell activation genes differentially expressed at birth in CD4+ T-cells from children who develop IgE food allergyTo show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy.
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Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive DevelopmentNew research links poor language to lack of Vitamin D in womb.
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A genomics-based approach to assessment of vaccine safety and immunogenicity in childrenThis methodology has significant potential to identify covert interactions between inflammatory pathways triggered by vaccination, and as such may be a...
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Hospitalisation for bronchiolitis in infants is more common after elective caesarean deliveryThe authors previously reported an increased risk of hospitalisation for acute lower respiratory infection up to age 2 years in children delivered by...
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T regulatory cells in childhood asthmaAsthma is a chronic disease of the airways, most commonly driven by immuno-inflammatory responses to ubiquitous airborne antigens.