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Bronchopulmonary dysplasia: Rationale for a pathophysiological rather than treatment based approach to diagnosisThis review describes the evolution of bronchopulmonary dysplasia definitions, evaluates the benefits and limitations of each approach
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Bronchodilator responsiveness in children with asthma is not influenced by spacer device selectionSpacer device was not associated with clinically important differences in lung function following bronchodilator inhalation in children with asthma
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Laryngeal reflex responses in pediatric anesthesiaLaryngeal and respiratory reflexes are vitally important defense mechanisms against foreign body aspiration, safeguarding airway patency, and ventilation
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Association between diesel engine exhaust exposure and lung function in Australian gold minersDiesel engine exhaust exposures were higher in underground miners and had a negative association with their lung function over a single 12-h shift
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Variants associated with HHIP expression have sex-differential effects on lung functionLung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females.
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Nasal airway epithelial repair after very preterm birthNasal epithelial cells from very preterm infants have a functional defect in their ability to repair beyond the first year of life, and failed repair may be associated with antenatal steroid exposure.
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No association between in utero exposure to emissions from a coalmine fire and post-natal lung functionStudies linking early life exposure to air pollution and subsequent impaired lung health have focused on chronic, low-level exposures in urban settings. We aimed to determine whether in utero exposure to an acute, high-intensity air pollution episode impaired lung function 7-years later.
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Living with lung disease: experimental models to assess the long-term effects of prematurityLaboratory models provide an important tool in helping to understand the cellular and molecular drivers of respiratory disease. Many animal models exist that model the neonatal outcomes of preterm birth.
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Feasibility of unsedated lung MRI in young children with cystic fibrosisKathryn Ramsey BSc (Hons), PhD Co-Head, Children's Lung Health kathryn.ramsey@thekids.org.au Co-Head, Children's Lung Health Associate Professor
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Altered lung structure and function in mid-childhood survivors of very preterm birthTo obtain comprehensive data on lung structure and function in mid-childhood from survivors of preterm birth.