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novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunctionThis study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability
Research
B Part of It School Leaver protocol: an observational study to assess the impact of a meningococcal serogroup B vaccine programme on carriage of Neisseria meningitidisThis study will assess the impact of MenB vaccine (4CMenB) on carriage prevalence in school leavers in South Australia
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Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthoodThese data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course
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Gender-affirming hormones and surgery in transgender children and adolescentsThis Review explores the available published evidence on gender-affirming cross-sex hormone and surgical interventions in transgender children
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Still keen and committed: piloting an instrument for identifying positive veteran teachersInitial findings suggest the potential of the instrument in helping identifying positive veteran teachers within systems, as well as the voracity of the research approach
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Does perinatal exposure to exogenous oxytocin influence child behavioural problems and autistic-like behaviours to 20 years of ageThis study is the first to investigate longitudinal mental health outcomes associated with the use of oxytocin-based medications during labour
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Effect of ten-valent pneumococcal conjugate vaccine introduction on pneumococcal carriage in Fiji: results from four annual cross-sectional carriage surveysDirect and indirect effects on pneumococcal carriage post-PCV10 are likely to result in reductions in pneumococcal disease, including in infants too young to be vaccinated
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Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early lifeIntra-breath forced oscillation technique can identify healthy infants at risk of developing LRTI, wheezing or severe illness in the first year of life
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Delay in commencement of palliative care service episodes provided to Indigenous and non-Indigenous patientsAlthough the timeliness benchmark is being met for Indigenous Australians in palliative care, they may experience delayed initiation of care episodes
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A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia PathogenesisHere we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia