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Research
Variants associated with HHIP expression have sexdifferential effects on lung functionLung function is highly heritable and differs between the sexes throughout life. However, little is known about sexdifferential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females.
Research
The PELICAN (Prematurity's Effect on the Lungs In Children and Adults Network) ERS Clinical Research Collaboration: understanding the impact of preterm birth on lung health throughout lifeAn estimated 15 million babies (∼11%) are born preterm each year (before 37 weeks of gestation), the rates of which are increasing worldwide. Enhanced perinatal care, including antenatal corticosteroids, postnatal surfactant and improved respiratory management, have markedly improved survival outcomes since the 1990s, particularly for babies born very preterm (<32 weeks gestation). However, long-term pulmonary sequelae are frequent in preterm survivors and ongoing clinical management is often required.
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Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical StatementStandards and consensus recommendations are presented for manufacturers, clinicians, operators, and researchers
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Reduced forced vital capacity in Aboriginal Australians: Biology or missing evidence?This editorial article addresses chronic obstructive pulmonary disease and lung function testing in Aboriginal Australians.
Research
Age- and height-based prediction bias in spirometry reference equationsPrediction bias in spirometry reference equations can arise from combining equations for different age groups,...
Research
Influence of gestational age on dead space and alveolar ventilation in preterm infants ventilated with volume guaranteeVentilated preterm infant lungs are vulnerable to overdistension and underinflation.
Research
Respiratory impedance in healthy unsedated South African infants: Effects of maternal smokingNon-invasive techniques for measuring lung mechanics in infants are needed for a better understanding of lung growth and function...
Research
Progressive ventilation inhomogeneity in infants with cystic fibrosis after pulmonary infectionThis study aimed to determine how pulmonary inflammation & infection impacts on ventilation distribution throughout early life in people with cystic fibrosis.
Research
Interpretation of lung function in infants and young children with cystic fibrosisThis paper is a review of lung function tests best suited to use for early detection of lung disease in Cystic Fibrosis.
News & Events
Lung study helps history-making generation get a handle on their healthA lung function study carried out by Dr Shannon Simpson provided the most comprehensive follow-up of very pre-term children of any study so far carried out on the lung health of this vulnerable group.