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Research

Cochrane corner: hearing aids for mild to moderate hearing loss in adults

The evidence supports the widespread provision of hearing aids as the first-line clinical management for those seeking help for hearing difficulties

Research

Tryptophan and arginine catabolic enzymes and regulatory cytokines in clinically isolated syndrome and multiple sclerosis

Higher IDO and ARG expression in clinically isolated syndrome and multiple sclerosis provides one sustained homeostatic mechanism to control multiple sclerosis-associated inflammation

Research

Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome

IgG3 levels and proportions of IgG3 (%IgG) in serum at CIS diagnosis were inversely correlated with the time until conversion to MS

Research

Comprehensive investigation of congenital anomalies in cerebral palsy: Protocol for a European-Australian population-based data linkage study

The aim of this study is to generate new knowledge about the aetiologies of CP through a focused investigation into the role of congenital anomalies

Research

Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma

Airway interleukin-33 is associated with type-2 cytokines in naturally occurring asthma exacerbations in adults

Research

Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular Mimicry

Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells.

Research

A pathogenic role for the integrin CD103 in experimental allergic airways disease

Role for CD103 in the pathogenesis of experimental allergic airways disease in BALB/c mice through local control of CD4+ T cell and DC subset recruitment

Research

Influenza C infections in Western Australia and Victoria from 2008 to 2014

Comparison of Influenza C viruses detected from Australian clinical samples with Influenza C viruses detected in other parts of the world in recent years

Research

Efficacy of infant simulator programmes to prevent teenage pregnancy: a school-based cluster randomised controlled trial in Western Australia

The infant simulator-based Virtual Infant Parenting programme did not achieve its aim of reducing teenage pregnancy