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Antisense oligonucleotides are an emerging therapeutic option to treat diseases with known genetic origin. In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing. Antisense oligonucleotides can alter gene expression through a variety of mechanisms as determined by the chemistry and antisense oligomer design.
Four outstanding members of The Kids Research Institute Australia family have been named as finalists in the 2024 Western Australian of the Year Awards.
The Kids Research Institute Australia researchers have been awarded more than $8 million in prestigious project grants from the NHMRC.
New funding from the Stan Perron Charitable Foundation will support innovative research projects and programs at The Kids Research Institute Australia with the aim of improving the health and wellbeing of WA children and their families.
A third of Western Australian one-year-olds and up to two thirds of three-year-olds have low iron, a study by The Kids Research Institute Australia has found.
ORIGINS sub-project, The Flourishing Child, has received a $746,051 grant from the Medical Research Future Fund to develop a Flourishing Assessment and Pathway Tool to address gaps in early intervention for children's mental health.
ORIGINS is celebrating a substantial funding increase for its world-class research into child and family health and wellbeing.
The Kids Research Institute Australia researchers have been awarded five of eight State Government awards designed to help cover the hidden costs of conducting research.
Western Australia experiences multiple climatic zones, influencing the epidemiology of respiratory viruses. We aimed to estimate the true incidence of respiratory syncytial virus and influenza hospitalizations across these different climatic regions using predictive modelling.
Between January 2022 and December 2023, there were 1,827 bloodstream infection (BSI) isolates in 1,745 children and adolescents reported to the Australian Group on Antimicrobial Resistance (AGAR) surveillance outcome programs, with 40% of episodes in children aged < 12 months.