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Research

Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16

Though HRVs are usually innocuous viruses, they can trigger serious consequences in certain individuals, especially in the setting of IFN synthesis.

Research

REACH: study protocol of a randomised trial of rehabilitation very early in congenital hemiplegia

Congenital hemiplegia is the most common form of cerebral palsy (CP). Children with unilateral CP show signs of upper limb asymmetry by 8 months corrected age (ca) but are frequently not referred to therapy until after 12 months ca. This study compares the efficacy of infant-friendly modified constraint-induced movement therapy (Baby mCIMT) to infant friendly bimanual therapy (Baby BIM) on upper limb, cognitive and neuroplasticity outcomes in a multisite randomised comparison trial.

Research

The importance of the exposome and allostatic load in the planetary health paradigm

The concept of planetary health emphasizes that human health is intricately connected to the health of natural systems within the Earth's biosphere

Research

Adolescents' Perspectives on a Mobile App for Relationships: Cross-Sectional Survey

Adolescents were likely to use a mobile phone app for relationship support, and use was not influenced by background characteristics

Research

Discovery of Transcription Factors Novel to Mouse Cerebellar Granule Cell Development Through Laser-Capture Microdissection

This study provides an initial insight into the TFs of cerebellar granule cells that might be important for development

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Incidence of childhood onset type 1 diabetes in Western Australia from 1985 to 2016: Evidence for a plateau

This study provides evidence for a possible plateauing in the incidence of childhood T1D in Western Australia, following a peak in 2003

Research

Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: a pooled analysis from the childhood Leukemia International Consortium

Our findings suggest that high coffee intake during pregnancy may increase risk of childhood acute lymphoblastic leukemia

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Living on a farm, contact with farm animals and pets, and childhood acute lymphoblastic leukemia

These findings add additional evidence to the hypothesis that regular contact with animals in early childhood is inversely associated with childhood acute lymphoblastic leukemia

Research

Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis

We think that variants in genes involved in fructose metabolism and ChREBP-FGF21 pathway interacts with SSB intake to exacerbate associations with SSB intake.

Research

Identification of health risk behaviours among adolescent refugees resettling in Western Australia

We aim to identify health risk behaviours among adolescent refugees resettling in WA and assess the feasibility of using a standardised questionnaire.