Skip to content
The Kids Research Institute Australia logo
Donate

No results yet

Search

Research

Subgroups of Temperament Associated with Social-Emotional Difficulties in Infants with Early Signs of Autism

Links between temperament and social-emotional difficulties are well-established in normative child development but remain poorly characterized in autism. We sought to characterize distinct temperament subgroups and their associations with concurrent internalizing and externalizing symptoms in a sample of 103 infants showing early signs of autism.

Research

Repair of an Attenuated Low-Passage Murine Cytomegalovirus Bacterial Artificial Chromosome Identifies a Novel Spliced Gene Essential for Salivary Gland Tropism

The cloning of herpesviruses as bacterial artificial chromosomes (BAC) has revolutionized the study of herpesvirus biology, allowing rapid and precise manipulation of viral genomes. Several clinical strains of human cytomegalovirus (HCMV) have been cloned as BACs; however, no low-passage strains of murine CMV, which provide a model mimicking these isolates, have been cloned. Here, the low-passage G4 strain of was BAC cloned. G4 carries an m157 gene that does not ligate the natural killer cell-activating receptor, Ly49H, meaning that unlike laboratory strains of MCMV, this virus replicates well in C57BL/6 mice.

News & Events

Mixed results for late talking toddlers

Findings from the world's largest study on language emergence have revealed that one in four late talking toddlers continue to have language problems at age 7

News & Events

International award for Rett syndrome research

A Perth medical researcher responsible for major advancements in the understanding of the neurological disorder Rett syndrome has had her efforts recognised

News & Events

Bird flu vaccine produces promising results

An Australian-developed vaccine that's been trialed in Perth has been found to produce a strong immune response against the H5N1 bird flu virus.

News & Events

Little improvement in Aboriginal educational performance

The most comprehensive survey every undertaken of Aboriginal education has found little significant improvement in outcomes for children in more than 30 years

News & Events

Folate commitment will protect babies

Child health expert Professor Fiona Stanley has welcomed today's commitment to proceed with mandatory fortification of food with folate.

News & Events

Meningitis study aims for fewer needles

Perth researchers are investigating a new combined vaccine to protect against three causes of potentially deadly bacterial meningitis.

News & Events

Perth researchers test stress link to asthma

Scientists at The Kids for Child Health Research have launched an innovative project to test the relationship between stress and asthma.

News & Events

Researchers tackle big issues in child development

Perth's The Kids for Child Health Research has been awarded a major national grant to continue ground-breaking work on child health and development.

News & Events

International study looking at Kawasaki Disease

Perth researchers are leading an exciting new international study looking at genetic factors that may cause Kawasaki disease and the subsequent heart damage.

News & Events

Researchers find genetic clue to cancer relapse

Cancer researchers at The Kids for Child Health Research have developed a new test that can rapidly detect the loss of genes in cancer cells.

Research

Ambient Air Pollution, Extreme Temperatures and Birth Outcomes: A Protocol for an Umbrella Review, Systematic Review and Meta-Analysis

Prenatal exposure to ambient air pollution and extreme temperatures are among the major risk factors of adverse birth outcomes and with potential long-term effects during the life course. Although low- and middle-income countries (LMICs) are most vulnerable, there is limited synthesis of evidence in such settings. This document describes a protocol for both an umbrella review (Systematic Review 1) and a focused systematic review and meta-analysis of studies from LMICs (Systematic Review 2).

Research

Financial Interventions to Increase Vaccine Coverage

Recent vaccine mandates in Australia, as in other high income settings, have sought to change the behavior of parents, including those who would otherwise access nonmedical exemptions. Since 2014, Australian state governments have introduced and progressively tightened policies restricting the access of unvaccinated children to early education and child care.