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Research

Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease

Research

Adverse metabolic phenotype of adolescent girls with non-alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boys

Non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) share risk associations of adiposity and insulin resistance.

Research

Strabismus, a preventable barrier to social participation: A short report

Isolated strabismus does not significantly impair visual functionality and has traditionally been considered a primarily cosmetic defect of little importance.

Research

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

Our results reveal the complexity of Leishmania donovani evolution in the Indian subcontinent in response to drug treatment

Research

A validation study of a modified Bouchard activity record that extends the concept of 'uptime' to Rett syndrome

The aim of this study was to investigate the validity of using a Bouchard activity record (BAR) in individuals with Rett syndrome to measure physical...

Research

Can skin exposure to sunlight prevent liver inflammation?

Here we discuss how skin exposure to sunlight may suppress liver inflammation and the severity of NAFLD.

Research

Mechanisms of allergic disease - environmental and genetic determinants for the development of allergy

Environmental exposures including maternal inflammation, diet, nutrient balance, microbial colonization and toxin exposures can directly and indirectly...

Research

Environmental health challenges in remote Aboriginal Australian communities: clean air, clean water and safe housing

A considerable health disparity exists between Aboriginal and non-Aboriginal Australians, including a higher incidence and severity of cardiovascular and...

Research

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

Our data support a highly generalizable model in which enhancer transcription is the earliest event in successive waves of transcriptional change during...