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Research

Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity

Our result highlighted that miRNA-target gene network contributes to human disease genetics in a cell type-specific manner

Research

Intellectual disability and psychotic disorders in children: Association with maternal severe mental illness and exposure to obstetric complications

Maternal severe mental illness and exposure to obstetric complications contribute separately to the risk of intellectual disability

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Construct validity and responsiveness of the functional Tactile Object Recognition Test for children with cerebral palsy

The functional Tactile Object Recognition Test demonstrated preliminary construct validity, and was positively associated with an upper limb activity measure

Research

Age at menarche and childhood body mass index as predictors of cardio-metabolic risk in young adulthood: A prospective cohort study

Earlier age at menarche may be indicative of a higher risk profile for cardiovascular disease in young adulthood

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Are children more vulnerable to mesothelioma than adults?

We found no greater susceptibility to mesothelioma among those first exposed to asbestos as children than those first exposed as adults

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Predicting disease progression in cystic fibrosis

Comprehensive scores incorporating clinical, lung function, imaging and laboratory data will become essential in the future for predicting disease progression and for use in clinical trials

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Parent-reported health-related quality of life of children with Down syndrome: A descriptive study

To describe health-related quality of life of Australian children and adolescents with Down syndrome and compare it with norm-referenced data.

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Rheumatic heart disease in Timor-Leste school students: an echocardiography-based prevalence study

The rates of RHD in Timor-Leste are among the highest in the world, and prevalence is higher among girls than boys

Research

Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 study

The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average