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A call to action: the second Lancet Commission on adolescent health and wellbeing

Adolescents are the future leaders of our world. Ensuring their health and wellbeing—now and in the future—is one of the strongest mechanisms available to safeguard the collective future of humanity and to secure a more just society and a healthier and more productive planet. 

Age-related differences in trust beliefs during middle childhood: Downward-extension and validation of the general trust scale

There are conflicting suggestions concerning the developmental trend of trust beliefs during middle childhood. Across three studies, the current research developed a brief measure of child general trust beliefs, as well as child measures of trust in peers and online, and examined age-related differences in these beliefs. 

Single-cell data combined with phenotypes improves variant interpretation

Whole genome sequencing offers significant potential to improve the diagnosis and treatment of rare diseases by enabling the identification of thousands of rare, potentially pathogenic variants. Existing variant prioritisation tools can be complemented by approaches that incorporate phenotype specificity and provide contextual biological information, such as tissue or cell-type specificity. 

Maternal vitamin D status during pregnancy and bone mass in offspring at 20 years of age: A prospective cohort study

This longitudinal, prospective study investigated the association between maternal vitamin D status and peak bone mass of offspring in 341 mother and...

'I can sit and talk to her': Aboriginal people, chronic low back pain and healthcare practitioner communication

Chronic low back pain (CLBP) is a complex issue to manage in primary care and under-researched in Aboriginal populations.

Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of age

This paper examines whether a Vitamin D deficiency during pregnancy affects the child's lung function predisposition towards lung disease such as asthma.

Maternal alcohol consumption during pregnancy and the risk of orofacial clefts in Infants: A Systematic Review and Meta-Analysis

This paper evaluated the association between maternal consumption of alcohol during pregnancy and the occurrence of cleft lip and palates in infants by...

Mesothelioma risk after 40 years since first exposure to asbestos: A pooled analysis

This paper discusses the risk of developing malignant mesothelioma more than 40 years after the first exposure to asbestos.

Route of exposure alters inflammation and lung function responses to diesel exhaust

In this study, we compared the physiological consequences of short-term exposure to diesel exhaust via inhalation to those due to exposure to the same diesel...

Solar ultraviolet radiation in a changing climate

This review article examines risks and benefits of exposure to ultraviolet radiation for the environment and human welfare.