Search
Research
Modeling COVID-19 disease processes by remote elicitation of causal Bayesian networks from medical expertsCOVID-19 is a new multi-organ disease causing considerable worldwide morbidity and mortality. While many recognized pathophysiological mechanisms are involved, their exact causal relationships remain opaque. Better understanding is needed for predicting their progression, targeting therapeutic approaches, and improving patient outcomes. While many mathematical causal models describe COVID-19 epidemiology, none have described its pathophysiology.
Research
A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancerMolecular profiling of the tumour immune microenvironment (TIME) has enabled the rational choice of immunotherapies in some adult cancers. In contrast, the TIME of paediatric cancers is relatively unexplored. We speculated that a more refined appreciation of the TIME in childhood cancers, rather than a reliance on commonly used biomarkers such as tumour mutation burden (TMB), neoantigen load and PD-L1 expression, is an essential prerequisite for improved immunotherapies in childhood solid cancers.
Research
Mental wellbeing in non-ambulant youth with neuromuscular disorders: What makes the difference?Mental wellbeing was independently associated with academic achievement and perceived family support but not with physical health variables
Research
Nicotine and other potentially harmful compounds in "nicotine-free" e-cigarette liquids in AustraliaThe aim of our investigation was to assess the chemical composition of a range of e-liquids available in Australia, focusing on nicotine and other potentially harmful compounds
Research
The Safety of Influenza and Pertussis Vaccination in Pregnancy in a Cohort of Australian Mother-Infant Pairs, 2012-2015: The FluMum StudyNo significant associations were found between maternal inactivated influenza vaccine or pertussis vaccination in pregnancy and adverse birth outcomes
Research
Risks and obstacles in implementing a public health approach to the wellbeing and protection of childrenWe have also been engaged with and excited by the attempts to adopt a public health approach to the care and protection of children as described throughout this book
Research
Emerging diabetes and metabolic conditions among Aboriginal and Torres Strait Islander young peopleCollaboration between clinicians and researchers is required to establish the prevalence and disease burden of type 2 diabetes among Indigenous young people
Research
Allergy alerts — The incidence of parentally reported allergies in children presenting for general anesthesiaOnly the minority of parent-reported allergies in pediatric surgical patients were specialist confirmed and likely to be clinically relevant
Research
Vaccine discussions in pregnancy: interviews with midwives to inform design of an intervention to promote uptake of maternal and childhood vaccinesWe explored midwives' attitudes and values regarding maternal and childhood vaccination, their perceived role in vaccine advocacy
Research
Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancersWe demonstrated the efficacy of FPPa-OmoMYC in inhibiting breast cancer growth when injected orthotopically in TNBC allografts